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26-26 Sep 2025 PARIS (France)
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Keynote speakersMARK ASCH (LAMFA-CNRS, University of Picardy)
 Mark Asch is emeritus professor of applied mathematics, attached to LAMFA-CNRS, University of Picardy. He has a long experience of teaching and research in the domains of inverse problems, digital twins and the application of machine learning. He is actively involved in the NUMPEX project, where work is being done on a continuum digital twin for wide-area, cross-facility workflows at exascale. He has held posts of responsibility at the French Ministry of Research, ANR, CNRS and at Total Energies. He has published numerous papers as well as two recent books on data assimilation and digital twins.
ANNA NIARAKIS (University of Toulouse III-Paul Sabatier)
 Dr Anna Niarakis is a Full Professor of Computational Systems Biology at the University of Toulouse III-Paul Sabatier, affiliated with the Center of Integrative Biology and the Laboratory of Molecular and Cellular Dynamics. She holds a 4-year delegation for research at INRIA- Saclay, in the group Lifeware.
Dr Niarakis has a broad scientific background in Biochemistry, Biology, Pharmaceutical Technology and post-doctoral studies in Computational Systems Biology and Bioinformatics (ENS, Paris, Institut Gustave Roussy) with expertise in complex human diseases, especially autoimmune diseases. She is a co-leader of the Disease Maps consortium coordinating the COVID-19 Disease Map initiative, and she also leads the Working Group “ Building Immune Digital Twins”, supported by the Research Data Alliance. Dr Niarakis has significant expertise in academic teaching and mentoring, course design and management and is also very active in organizing and participating in international summer and winter schools of Computational Systems Biology. She is the main co-organizer and the leading instructor of the Wellcome Trust Advanced Course "Computational Systems Biology for Complex Human Disease: From Static to Dynamic Representations of Disease Mechanisms" KRISTIN REICHE (Fraunhofer Institute for Cell Therapy and Immunology IZI, Leipzig) Kristin Reiche is Head of the Department of Medical Bioinformatics at the Fraunhofer Institute for Cell Therapy and Immunology (IZI) in Leipzig and a Principal Investigator at the Center for Scalable Data Analytics and Artificial Intelligence (ScaDS.AI) Dresden/Leipzig.
She combines omics-wide measurements—including single-cell and spatial transcriptomics profiling—with machine learning (ML), computational biology, and integrative bioinformatics to discover and validate biomarkers and therapeutic targets, especially for gene and cell therapies.
She is an expert in evaluating treatment responses to adoptive cellular immunotherapies using single-cell multi-omics data.
She also has experience in transferring ML models that interogate molecular data for personalized medicine, in compliance with the In Vitro Diagnostic Regulation (IVDR).
She coordinates the EU-funded project CERTAINTY — A cellular immunotherapy virtual twin for personalised cancer treatment (https://www.certainty-virtualtwin.eu/)
ATHINA PAPADOPOULOU (Research Data Alliance Europe)
She is supporting and facilitating the work of diverse RDA Working Groups from start to finish, ensuring the seamless adoption and uptake of their outputs. |
